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Meet the Professor Session: Osteoarthritis

Suneil Kapur, MD, BSc, Stephanie Myckatyn, MD, BSc

An international group of rheumatological and orthopedic healthcare professionals met with an osteoarthritis expert to discuss the non-pharmacological therapy of osteoarthritis. The workshop focused on the effects of osteoarthritis on the local joint environment of the knee. Few longitudinal studies have examined the effect of modifying the local environment on the progression of osteoarthritis.

Means of enhancing the local environment include:
 • Strengthening periarticular muscle (1)
 • Unloading disease compartments (2)
 • Improving proprioceptive acuity. (3)

Muscle strengthening is known to:
 • Protect the joint
 • Promote cartilage health and integrity
 • Protect knee tissues from injury
 • Provide joint stability.

Observational, cross-sectional studies have shown that strengthening exercises improve pain and function. The few longitudinal studies to date, focusing on strengthening exercises and osteoarthritis progression, are conflicting.

Another consideration is unloading the diseased compartment with bracing or wedge insole orthoses. These modalities reduce stress by shifting the joint contact force away from the diseased compartment. In a six-month prospective study, the knee brace group scored better than control on the WOMAC pain scale. While small, uncontrolled trials have demonstrated improved pain and function with wedge insole orthoses, no long-term studies exist.

Improvements in proprioceptive acuity lead to better spatial and temporal coordination of limb position. Methods include:
 • Elastic bandages
 • Braces
 • Neoprene sleeves.

There are no long-term studies assessing the effect of improved proprioception on disease progression.

Adjuncts to these modalities that may enhance impact on pain and function include:
 • Psychosocial support
 • Education
 • Medical therapy.

Overall, more longitudinal studies evaluating local joint interventions are required.

References
1. Sharma L, Lou C, Felson DT et al. Laxity in healthy and osteoarthritic knees. Arthritis Rheum 1999;42:861 - 870.
2. Kirkley A, Webstr-Bogert S, Litchfield R et al. The effect of bracing on varus gonarthrosis. The Journal of Bone and Joint Surgery 1999;81A(4):539 - 548.
3. Polo F. Bracing and heel wedging for unicompartmental osteoarthritis of the knee. The American Journal of Knee Surgery 1998;11:47 - 50.
4. Van Baar ME, Assendelft WJJ, Dekker J et al. Effectiveness of exercise therapy in patients with OA of the hip or knee, a systematic review of randomized clinical trials. Arthritis and Rheum 1999;43:1361 - 1369.
5. Sharma L. Proprioceptive impairment in knee osteoarthritis. Rheumatic Disease Clinics of North America 1999;25:299 - 314.
6. Ogata K, Yasunaga M, Nomiyama H. The effect of wedged insoles on the thrust of osteoarthritic knees. International Orthopedics (SICOT) 1997;21: 308 - 312.

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